Title:Probing and manipulating the neural mechanisms underlying internal models of self-motion using high-density read-write electrode technology

The nodulus and uvula in the posterior cerebellar vermis receives substantial vestibular input both directly and indirectly. It has been previously studied during passive vestibular stimulation alone (whole-body motion). However to date, if or how the NU responds to other sensory information is unknown. Because the vestibular organs are located in the head, it is essential for the brain to use other cues to determine how the body is moving, and to generate appropriate motor commands during passive unexpected vestibular stimulation based on different body configurations. Here we find that NU Purkinje cells do integrate both static and dynamic neck proprioceptive information to encode self-motion and adjust cerebellar output based on the configuration of the head on the body.